{"gap":{"gap_id":"OEG-ONC-002","case_id":"SE-ONC-NSQNSCLC-CN-001","case_title":"China Non-Squamous NSCLC Evidence Pathway","case_url":"https://structurevidence.org/cases/nsq-nsclc-china/","claim_id":"SE-ONC-NSQNSCLC-CN-001.IVONESCIMAB_APPROVAL","claim_text":"Ivonescimab with pemetrexed and carboplatin was approved in China for the defined post-EGFR-TKI non-squamous NSCLC indication.","current_state":"SUPPORTED","current_scope":"Population-level regulatory status in China for EGFR-mutated locally advanced or metastatic non-squamous NSCLC progressing after EGFR-TKI; other populations, treatment lines, combinations, and jurisdictions are outside this claim.","evidence_cutoff":"2026-09-28","what_is_established":["An official NMPA public record supports approval of ivonescimab with pemetrexed and carboplatin for the defined China indication."],"what_is_not_established":["Approval for populations, treatment lines, combinations, or jurisdictions outside the regulator-defined scope","Comparative superiority or outcome claims beyond the cited evidence"],"what_would_change_this":"An official regulator record that changes, narrows, expands, suspends, withdraws, or corrects the approval status, label, combination, population, or treatment-line scope; or an authoritative correction or retraction of the cited regulatory source.","acceptable_source_examples":["NMPA approval label or official indication update","Official regulator safety, suspension, withdrawal, or correction notice","Authoritative source correction tied to the cited approval"],"non_qualifying_examples":["Manufacturer commercial copy","Media summary without a regulator record","Trial result alone without a regulatory action","Approval in another jurisdiction","Unverified drug database entry"],"last_reviewed":"2026-10-05","challenge_url":"https://structevidence.com/gaps/OEG-ONC-002/"},"change_log":[{"change_id":"OEG-CHANGE-006","gap_id":"OEG-ONC-002","challenge_id":null,"change_type":"GAP_OPENED","summary":"Initial open evidence gap published under Open Evidence Gap Protocol v0.1.","attribution":"StructEvidence","previous_state":null,"new_state":"SUPPORTED","changed_at":"2026-10-05","append_only":true}],"no_auto_state_change":true}